维生素E能降低患肝癌几率

 ,To determine the relationship between vitamin E intake and liver cancer risk, Wei Zhang, MD, MPH., of the Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine and colleagues analyzed ² data from a total of 132,837 individuals in China who were enrolled ³ in the Shanghai Women's Health Study (SWHS) from 1997-2000 or the Shanghai Men's Health Study (SMHS) from 2002-2006, two population-based cohort studies jointly ⁴ conducted by the Shanghai Cancer Institute and Vanderbilt University. Using validated ⁵ food-frequency questionnaires, the researchers conducted in-person interviews to gather data on study participants' dietary habits. They compared liver cancer risk among participants who had high intake of vitamin E with those with low intake., ,The analysis included 267 liver cancer patients (118 women and 149 men) who were diagnosed between 2 years after study enrollment ⁶ and an average of 10.9 (SWHS) or 5.5 (SMHS) years of follow-up. Vitamin E intake from diet and vitamin E supplement use were both associated with a lower risk of liver cancer. This association was consistent among participants with and without self-reported liver disease or a family history of liver cancer. "We found a clear, inverse ⁷ dose-response relation between vitamin E intake and liver cancer risk," the authors write, noting a small difference between men and women in the risk estimate, which is likely attributable to fewer liver cancer cases having occurred among SMHS participants due to the shorter follow-up period. Overall, the take home message is that, "high intake of vitamin E either from diet or supplements was related to lower risk of liver cancer in middle-aged ⁸ or older people from China."